In a recent review about the effects of cannabinoids, it was reported that symptoms of fibromyalgia can be treated by Nabilone (synthetic cannabinoid-based drug) (Walitt, Klose, Fitzcharles, Phillips, & Häuser, 2016).
In another review, it was also shown that fibromyalgia-related pain can be treated by cannabinoids (Lynch and Campbell, 2011).
However, another review stated that there is a lack of evidence to declare that fibromyalgia-related symptoms can be treated by cannabinoids (Fitzcharles, Baerwald, Ablin, & Häuser, 2016).
One study found that cannabis use led to stiffness and pain reduction and increased relaxation, somnolence as well as a feeling of well-being in patients with fibromyalgia (Fiz et al., 2011).
In a subpopulation of patients with fibromyalgia, reduced pain perception was observed upon THC administration (2.5-15 mg). The authors proposed that this decreased pain perception can be due to the analgesic effect of THC (Schley et al., 2006).
In patients with fibromyalgia, improvement in pain reduction, and life quality were observed upon the use of the synthetic cannabinoid-based drug Nabilone (Skrabek, Galimova, Ethans, & Perry, 2008).